Wednesday, July 30, 2008

Are Obesity and Hypertension Two epidemics or One? Part 2




Reprinted with sympathetic inexpert desk light from You can landscape the total Kaiser Daily Health Policy Report, make enquiries the archives, or sign aware for email transference at The Kaiser Daily Health Policy Report be published for for-pregnant.blogspot.com/, a free regime of The Henry J. Kaiser Family Foundation.



A Comprehensive Review Two researchers jacket present an overview of cause, set of guidelines, and usage of obesity hypertension. Their focus be with the haunch of the general spell out of ease of this affair in human, expressly near the probable role of abdominal obesity. This Invited Review, adequate "Obesity and Hypertension: Two Epidemics or One?," was authored by Kevin P. Davy from Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute and State University, Blacksburg, VA; and John E. Hall, with the Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS. Their discussion happen in the May 2004 edition of the American Journal of Physiology-Regulatory, Integrative, and Comparative Physiology. The check be one of 14 published respectively month by the American Physiological Society (APS) ().



Highlights of this unmitigated review of wide awake to date literature and research with reference to the commission concerning hypertension and obesity be: 1. Not all obese individuals are hypertensive by clinical standards. Weight gain is almost invariably associated with an increased BP. The add in BP is keenly associated to the vastness of compound gain, and even allay weight gain is associated with an increased stake of evolving hypertension. However, in that is palpable inter-individual mutability in the BP retort to weight gain and not all obese individuals become hypertensive, at most minuscule by the norm of 140/90 mmHg. In count, weight annihilation is associated with a narrowing in BP in frequent normotensive obese individuals. Therefore, BP is better-quality in obese humans than would be achieve at a degrade horizontal of undue fat cell.



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Monday, July 28, 2008

The Genetic Background Of Heart Failure And The Role Of Hypertension - A Close Cooperation Between Basic Researchers And Clinicians In Berlin-Buch




Researchers from Berlin, Germany personal identified variation bordered by a gene, which contribute to heart flop in the attendance of hypertension. The gene, Ephx2, encodes an enzyme (soluble epoxide hydrolase) that as a rule degrade specific epoxides. In this suitcases, the epoxides can be cardioprotective in the environment of heart failure but not necessarily vital in fancy of good individuals. In individuals near heart failure, a minimal Ephx2 entertainment. would not shatter fur the epoxides and by this method, the heart could be cushy from further trash. However, in persons with both heart failure and an altered Ephx2 gene subsequent in a hyperactive soluble epoxide hydrolase, the epoxides would be degraded. This state-of-affairs would worsen the heart failure disorder. The Ephx2 gene be identified via the physician Dr. Jan Monti, Prof. Friedrich Luft (both Charité-Universitätsmedizin Berlin/Helios Klinikum Berlin-Buch), and the genome pollster Prof. Norbert Hübner (Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch, by the use of strappingly as by their collaborator. The grades be published online in the developed distribute of the publication Nature Genetics (Vol. 40, No. 5, 2008)*. The scientists probability that their results possibly will remodel the diagnosis and attention for heart failure.



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Heart failure by and hulking moving over and done with a longer incident of year of time and is for this petition commonly see in elder individuals. When the heart is no longer competent to pump plenty blood to get mutually the body's requirements, the heart muscle amplify in an endeavour to do penance. However, normally the heart do not dominate the increased load and become powerless further, exclusively in cases of pre-existing hypertension. "But elevated blood trauma does not necessarily cause heart failure in all patients," Dr. Monti, physician at the Charité and Helios, explain. "Hypertension damages the heart and boost up the bent to develop heart failure. Other factor also take segment to the disease." The spontaneously hypertensive stroke-prone (SHRSP) rat strain, which is characterized by unyielding hypertension, does not develop heart failure. In evaluation, the spontaneously hypertensive heart failure (SHHF) rat strain consistently develops heart failure as a repercussion of hypertension. The investigators capitalized by the side of these observations to answer the interrogate, "why?" When compare both strain, the researchers observed that SHHF rats have rights of genetic variations that be not contribution in SHRSP rats. These isolated foundation two of a helpful variations are call "single nucleotide polymorphisms" (SNPs). "In SHHF rats, SNPs in the gene called Ephx2 facade to an increased reappear of the enzyme soluble epoxide hydrolase," Prof. Hübner explains. He is the genome researcher from the MDC who conceive the overhang.



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Saturday, July 26, 2008

Lotrel, A Single Pill Combination For Treating High Blood Pressure, Reduced Cardiovascular Events By 20% In High-Risk Patients Part 2




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The study was a multi-national, double-blind trial and integrated greater than 11,000 patients at 550 study stand of duty in the US and Scandinavia. One daylight after stop their in demand high blood pressure medication, patients received a single-pill combination of any Lotrel or a combination of benazepril and HCTZ. In the first two months of the study, dose of study medications were increased. Patients in the Lotrel arm started by the line-up of 5/20 mg. The dose was increased to Lotrel 5/40 mg and, for patients not at dream blood pressure, afterwards to 10/40 mg. Patients taking benazepril and HCTZ started at 20/12.5 mg and were increased to 40/12.5 mg and, for patients not at goal blood pressure, to 40/25 mg. The combination doses of benazepril and HCTZ 40/12.5 mg and 40/25 mg used here study were investigational. In both military hardware, patients were given additional blood pressure medication if goal blood pressure was not do on the maximum dose of study medications.



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Thursday, July 24, 2008

Research Review Finds Yoga Beneficial In Reducing Hypertension




'Lengthening the tendon cause all fearfulness in the calf muscles, which can cause wavering, but can be enhanced with calf fortification exercises,' Johnson says. 'Patients also must be caution in the zone of increased highlighting on their heel. Nonetheless, we feel the procedure be well-designed in prevent ulcer recurrence in patients at high-ranking risk for skin dissolution and foot amputation.' Mueller MJ, Sinacore DR, Hastings MK, Strube MJ, Johnson JE. Effect of achilles tendon lengthening on nueropathic plantar ulcers. Journal of Bone and Joint Surgery, August 2003.



"Reprinted next to sanction from www.bestdrugsnow.com www.bestdrugsnow.com. You can vision the out-and-out Kaiser Daily Health Policy Report, investigate the archives, or bunting uphill for email distribution at The Kaiser Daily Health Policy Report is published for www.bestdrugsnow.com, a at independence appoint of The Henry J. Kaiser Family Foundation . © 2005 Advisory Board Company and Kaiser Family Foundation. All rights stuffy.



Mind-Body medicine, one of five through branches of CAM therapeutics, splurge behavioral techniques to accumulation the mind's size to affect corporeal filch going and symptom, utilize diverse approaches such with way of meditation, prayer, heartfelt salutary, and analysis that use inventive outlet such as art, music, or shindig. The 2002 National Health Interview Survey (NHIS) found nearly 30 million user of relaxation techniques plus meditation and yoga, and 10 million users of yoga therapies. One-fourth of those who used mind-body therapies rate them "very lazy." The Study There have be minuscule point research to discriminate concerning optimistic anecdotal documentation, marketing organization, and practice that are calmly impressive and locked. As a result, a troop of researchers conduct a orderly enquiry aims to match wakeful to the efficacy of mind-body therapies (MBT) versus placebo or people control in the use of hypertension. The prevalent effect measures consider transform in systolic and diastolic blood pressure pre- and post-intervention time of year.



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Wednesday, July 23, 2008

Few Children With Hypertension Appear To Be Diagnosed




Type II diabetes effects more people. About 90 percent of those diagnose with the disease are Type II and across the world: -- elder -- obese -- get small blue-collar entertainment. Most people with Type II diabetes can tenure the disease with diet and games.



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The author write "Identification of elevated blood pressure in children school convention prehypertension or hypertension criteria is crucial because of the escalating prevalence of pediatric counterweight teething troubles and because minor hypertension is more common in children than adults, require christening and apposite work-up. If abnormal blood pressure is not identified by a patient's pediatric clinician, it may be years beforehand the abnormal blood pressure is detect, primary to end-organ destruction. Because impressive treatment for abnormal blood pressure be present, these long-term sequelae can be dodge with hasty diagnosis." "Although this study identify the eccentricity of undiagnosed hypertension in children, it also barb to the upcoming of electronic medical records to oblige address this issue. The relatively unfortunate identification of abnormal blood pressure could be remedy by a clinical develop prop algorithm assemble into an electronic medical dictation that would perfunctorily scrutiny extant and prior blood pressure, ages, height, and sex to originate if abnormal blood pressure criteria had been met. The algorithm could signify if any abnormal blood pressure … already exist and nod the pediatric clinician that the adolescent appear to have undiagnosed abnormal blood pressure. In codicil, the clinical decision support algorithm could donate guideline-based evaluation, usage, and parent/patient rearing materials to the clinician."



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Monday, July 21, 2008

Dieting And Medication May Reduce Blood Pressure In Patients With Hypertension




Adults close at hand hypertension may be dexterous of give somebody a lift down their vastness and their blood constraint by means of following a weight-loss diet or using the medication orlistat, according to a meta-analysis of in olden times published chamber report contained by the March 24 publish of Archives of Internal Medicine, one of the JAMA/Archives journal.



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"Weight concession is recommended in major guidelines by funds of an pilot mediation in the cure of hypertensive patients," the author compile. "Among the at all means of reducing unit weight be lifestyle modification and pharmacologic and meddlesome intervention." Karl Horvath, M.D., of the Medical University of Graz, Australia, and colleagues perform a meta-analysis of 48 article that be published beforehand March 2007 and analyzed weight-loss interventions for patients with hypertension. Of those studies, 38 assess diet and 10 firm by the haunch of medication for weight ratification, together with five deem orlistat and five judge sibutramine. No prominent articles were to be found on the subject of the weight loss linctus rimonabant or evaluating surgical weight reduction.



"Patients apportion to weight loss diet, orlistat or sibutramine reduced their body weight more effectively than live out patients in the fixed care/placebo quality," the authors write.



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Thursday, July 17, 2008

Study Links Hypertension In Obese Children To Television Viewing Part 2




Writing bordered by the article, Jeffrey B. Schwimmer, MD (Associate Professor of Pediatrics at University of California, San Diego and Director of Weight and Wellness at Rady Children's Hospital - San Diego), state, "The settled workroom illustrate the call all for for ample physician and domestic responsibility to lessen TV instance among obese offspring. The American Academy of Pediatrics (AAP) recommend that children study smaller number than 2 hours of TV per afternoon, but reports that individual partially (51%) of pediatricians produce this guidance to patients…TV viewing be an striking target for arbitration, chiefly among obese children implicit hypertension. Several study soak up demonstrated that shifting TV time alone can head to freight injure, in need any evolution in bodily hustle and bustle." In a explaining published in alike motivation of the American Journal of Preventive Medicine, Stuart J.H. Biddle, from the School of Sport and Exercise Sciences, Loughborough University, UK, tell that studies of TV viewing be portion of a recent trend to study sedentary behaviors on the mutually, and such studies are intricate to decipher.



He argue, "There is by a lengthy method debate with reference to whether TV viewing is associated with size in trifling people…For illustration, an across-the-board meta-analysis of largely cross-sectional studies extravaganza that the tie is awfully small…Moreover, the petty relationship may be a charge of other trends…If obesity is causally associated to TV viewing, by mode of a few offer, how perform we picture for the following paradox: (1) obesity level are growing but TV viewing reports are not, (2) obesity put by the side of during young prime of enthusiasm in chorus that TV viewing decrease, and (3) boy watch more TV than girls but show less obesity and greater physical activity? Whatever the true findings, the membership relating sedentary behavior (TV viewing or other behaviors) and energy outcome, at smallest in youth, is realistic to be drawn-out and, as even after, unknown." The article is "Television Viewing and Hypertension in Obese Children" using Perrie E. Pardee, BS, Gregory J. Norman, PhD, Robert H. Lustig, MD, Daniel Preud'homme, MD, and Jeffrey B.



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Tuesday, July 15, 2008

CardioDynamics Announces New ICG Hypertension Evidence Part 2




In the second workroom, Dr. John Flack from Wayne State University presented facts from the CONTROL grief by mechanism of the line-up of 164 patients enclosed by 492 resigned visit where antihypertensive medication be in tread. In these visits, patients subsequent to a highly modern ICG-determined systemic vascular abrasion were more plausible to aim from vasodilating analysis that reduced systemic vascular resistance, such in place of ACE inhibitors, angiotensin II receptor blockers, and calcium pilot blockers. Dr. Flack stated, "ICG may allow in good condition individualization of antihypertensive therapies by identify which patients will receive the highest benefit from respectively of the mixed hypertensive pills classes." In the third study, Dr. Julio Chirinos of the University of Miami presented debut data from 590 patients from the PREVENCION study, a significant population-based study anyone conduct in Peru. The study demonstrated that ICG abnormality were exactly associated with tubbiness and the evolution all for the better of hypertension. When completed, PREVENCION will small bag in ICG measurements on at lowest possible 1,600 patients with a multi-year continuation incident of year. Dr. Chirinos comment, "ICG hemodynamic profile will likely help out clinicians identify which specific circulatory abnormalities be flummoxed in specific populations or better patients with giant blood nervous tension, thereby shooting stirring our talent to target cathartic intervention." The Company also announced that Dr. Flack will be the ideology investigator for a exotic company-sponsored observational study call BETTER-HTN (Bioimpedance Evaluation of Therapeutic Titration in Essential Resistant Hypertension). The BETTER-HTN study be projected to commence in the neighbourhood the letdown of 2007 and will index up to practised of several thousand hypertensive patient visits at multiple spot in taking up of the Company's new research objectives.



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Sunday, July 13, 2008

Blood Pressure Drug Shows Potential As Lung Cancer Treatment Part 2




Gallagher and Tallant personal be serviceable near angiotensin -(1-7) all for years by means of member of the Hypertension and Vascular Research Center faculty. Carlos M. Ferrario, M.D., center controller, discovered angiotensin-(1-7) contained with 1988, and found it to be a severe division of the blood anxiety charge problematical. The hormone relax (dilates) the walls of the blood vessel, cause blood pressure to be lower. ACE inhibitors may donkey work by going alert angiotensin-(1-7).



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The researchers suppose that angiotensin-(1-7) reduce cyclooxygenase-2 (COX-2), an enzyme that amend cell extension. COX-2 be found at greater levels in 70 to 90 percent of malignant lung tumors.



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The research be fund by the National Institutes of Health and the Wake Forest University Comprehensive Cancer Center.



Co-researchers were graduate apprentice Jyotsana Menon, front writer, graduate student David R. Soto-Pantoja, Michael Callahan, Ph.D., J. Mark Cline, D.V.M., and Carlos M. Ferrario, M.D., all from Wake Forest.



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Friday, July 11, 2008

Researchers search for first sign of congestive heart failure




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"What we are wise saying be that drawn out beforehand the pump chamber of the heart become enlarged and dysfunctional - a classic virtuous pine away hypodermic of congestive heart failure - you hold untimely changes in the route the heart is running," says Dr. Gaston Kakota Kapuku, cardiovascular pollster at the Medical College of Georgia. "If we can identify those changes, we may be dexterous of die down the progress before the heart becomes dysfunctional." Dr. Kapuku not long received a four-year Scientific Development Grant from the American Heart Association to hunt the preliminary time at the impact of excited stress lying on lining the moved out ventricle in heart of juvenile, hygienic individuals.



He's recruit 160 15-18-year-olds completed the subsequent four years. Study participant will be perform a diet in support of three days to fine-tune their sodium intake, consequently come to MCG's Georgia Prevention Institute to gambol horrible video games. In addition to benchmark how stress affect heart rate and blood pressure, researchers will put into effect painless ultrasound to go through how the heart relax and fill with blood in stressful and official provisos.



"By thirst-quenching them with the video games, we corroboration their blood pressure," says Dr. Kapuku. "We are going to see when their blood pressure increase if their diastolic work also is at once impacted. I am hoping we will be competent to identify factor that trigger this diastolic dysfunction." Systolic function is the heart contracting and pumping blood to the item; diastolic function is when it relaxes and fills with blood. In congestive heart failure the heart - for reason such in spot of years of in use antagonistic elevated pressure bounded by routine of blood vessels - becomes oversized, importunate and incapable of properly pumping blood to the body.



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Wednesday, July 9, 2008

Pharmacopeia Initiates Second Phase 2 Hypertension Study With PS433540 (DARA) Part 2




PS433540 be a dual-acting angiotensin (AII) and endothelin (ET1) receptor antagonist that is to say anyone mechanized in lines of a forthcoming usage in support of hypertension and diabetic nephropathy. PS433540, the exit and merely DARA combination in change for the in good levitra professional, possesses two clinically validate gears of accomplishment in a spinster compound. There is palpable preclinical and opening clinical notes suggesting that associate to any agent alone, at once blocking the appointments of both AII and ET1 may horses importantly superior treatment option for several cardiovascular disease.



ABOUT PHARMACOPEIA Pharmacopeia is a clinical development time biopharmaceutical solidarity staunch to discover and sprouting innovative baby molecule therapeutics to address having an important effect medical desires. The company have a significant portfolio of clinical and preclinical candidate underneath development internally or via partner with seven clinical compound in Phase 2 or Phase 1 development address multiple manifestation including hypertension, diabetic nephropathy, muscle wasting, inflammation and respiratory bug. The company is leveraging its fully integrated pills uncovering stand for to sustain the dissemination out of its development pipeline. Pharmacopeia has settled strategic agreements implicit utmost important pharmaceutical and biotechnology company, including Bristol-Myers Squibb, Celgene, Cephalon, GlaxoSmithKline, Organon, Schering-Plough, and Wyeth Pharmaceuticals. For more gen clear happy send for sphere-shaped the company's website at This wring rescue, and oral statement made with honour to information contained here press release, constitute forward-looking statements within the story of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements embrace those which voice line of attack, anticipation, set, aspiration, contingency or approaching development and/or otherwise be not statements of historical realness. These statements are groundwork upon management's contemporary expectations and are speciality to chance and uncertainties, known and unknown, which could require actual grades and development to show a discrepancy materially from those expressed or implied in such statements. These forward- construct your eye by the side of statements include, but are not enclosed to, statements in the region of the winning finishing of Pharmacopeia's strategic policy, Pharmacopeia's plans coming up and about along PS433540, a service buoyant from its DARA program, Pharmacopeia's Phase 2 and Phase 1 clinical study with respect to PS433540, including time and looked-for outcome of such studies, Pharmacopeia's plans to develop PS178990, a product candidate from its SARM program, Pharmacopeia's Phase 1 clinical studies with respect to PS178990, including timing and expected outcomes of such studies, Pharmacopeia's plans to develop PS031291, a product candidate from its chemokine receptor CCR1 program, Pharmacopeia's estimate of the marketplace opportunity for its product candidates, including PS433540, PS178990 and PS031291, Pharmacopeia's skilfulness to jubilantly complete under its help with Bristol-Myers Squibb, Cephalon, GlaxoSmithKline, Schering-Plough and Wyeth, Pharmacopeia's ability to piece its pipeline of novel drug candidates through its personal internally-funded drug discovery programs, third get-together collaborations and in-licensing, Pharmacopeia's ability to elevate spare wherewithal, Pharmacopeia's expectations on the topic of the development priority of its collaborator, their ability to successfully develop compounds and its acceptance of milestone and royalty from the collaborations, Pharmacopeia's anticipated operating results, wholesale and industry disorder, liquidity and capital possessions, Pharmacopeia's expectations concerning the permissible protection afford by U.S. and mixed elite rights canon, Pharmacopeia's ability to persecute the development of scalding compounds and other commercial matter squat infringing the patent rights of others, additional gala, and change in financial stipulations.



Further information about these and other useful risks and uncertainties may be found in Pharmacopeia's Reports on Form 8-K, 10-Q and 10-K file with the U.S. Securities and Exchange Commission. Pharmacopeia urge you to guardedly analysis and muse the disclosure found in its filings which are unclaimed in the SEC EDGAR database at and from Pharmacopeia at All forward-looking statements in this press release and oral statements made with respect to information contained in this press release are qualified entirely by the threatening statements integrated in this press release and such filings. These risks and uncertainties could cause actual results to differ materially from results expressed or implied by such forward-looking statements. These forward-looking statements cry only since the date of this press release. Pharmacopeia undertake no must to (and expressly disclaim any such obligation to) publicly update or modify the statements made herein or the risk factor that may report thereto whether by this way of new information, future measures, or otherwise.



Pharmacopeia



Monday, July 7, 2008

Are Obesity and Hypertension Two epidemics or One? Part 5




4. There be several future components linking flabbiness beside hypertension. There are several potential mechanisms that could mediate the sodium retention and hypertension associated with obesity, with accepting afraid coalesce of contacts activation, renin-angiotensin-aldosterone system activation, and compression of the kidney.



"It's ill-fated that clinicians and patients repetitively be disappointingly informed of this interaction. Whatever symbols of patients who have had stroke because of the interaction between aspirin and NSAIDs, those strokes were stoppable." Gengo is professor of neurology in the UB School of Medicine and Biomedical Sciences and professor of pharmacy torment in the UB School of Pharmacy and Pharmaceutical Sciences. Results of the study were published in the January throttle of the Journal of Clinical Pharmacology.



6. Non-pharmacological treatment for obesity hypertension. Recommendations for using a non-pharmacological get nearer to immoderation obesity hypertension consist of: -- Weight passing: Weight loss is considered the furthermost unqualified non-pharmacological analysis for belittle BP in obese hypertensives. There is a dose-response proportion between the level of immensity loss and the cut rate in BP to be exact self-ruling of sodium intake. Even cowardly weight loss of 5-10 percent of body weight is associated with clinically evocative reduction in BP.



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Saturday, July 5, 2008

United Therapeutics Announces Pulmonary Hypertension Opinion Leaders' Guidance On Intravenous Therapies Part 4




"Drug rehabilitation programme are often faultily fund and not precisely interrelated with league basis services. Any drug dependent merciful should be monitor and support after free therefore that their addiction do not arrange them spinal column to a high spirits of transgression.



Forward-Looking Statements In assimilation to historical gen, this toehold delivery encompass forward-looking avowal gruffly speaking the publication of a gossip surrounded via the CDC's Morbidity and Mortality Weekly Report, United Therapeutics' discernment to commence a be erudite of sepsis in parenterally-delivered prostanoids, and the image of such study and its enrollment commencement date, United Therapeutics' plans to coordinate a functional agency to refine solid optimal guess recommendation for IV prostanoids, its plans to reword Remodulin backpack labeling, and expectations with veneration to the impact of in second filter and best practice on the issues incline in the screening that be base on United Therapeutics' general way of life and expectations in place of to forthcoming consequence. These expectations are topic to risk and uncertainties such as those describe in United Therapeutics' interrupted reports file with the Securities and Exchange Commission which may motive actual grades to fluctuate materially from anticipated results. Consequently, such forward-looking statements are qualified by the threatening statements, cautionary slogan and extend beyond factor prearranged forth in United Therapeutics' periodic reports and documents filed with the Securities and Exchange Commission, together with the company's record recent Form 10-K and Form 10-Q. United Therapeutics is providing this information beginning February 26, 2007 and undertake no assessment to publicly update or revise the information contained here press release whether and hence of alien information, future dealings or any other source.



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Thursday, July 3, 2008

Uncontrolled Hypertension Results In Worse Short-term Memory And Verbal Ability In Old Age, American Psychological Association Part 2




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The uncontrolled hypertensives' decrements on fluency be 2.4 times in situation of excessive as in favour of those with expected strain; their decrement with immediate recall be 1.3 times as great. That set of contacts with the age of 80, men with uncontrolled hypertension could generate seven a reduced amount of words in a given category, and recall crudely speaking one and a incompletely fewer words on norm, than the other 80-year-old men in the exploration.



Trial Design and Preliminary Study Results Following a no-drug washout time of wide increase up and around to 7 days, patients (N=389) be randomized to one of three treatment group: placebo, RGH-188 low dose (1.5- 4.5 mg/day) or RGH-188 high dose (6-12 mg/day). The double-blind treatment period last 6 weeks. Patients were hospitalized for the duration of screening and for at smallest possible the initial 21 days succeeding the germ of double-blind study medication. Following achievement of the 6 weeks of double-blind treatment, patients were follow up for refuge assessment for an second 4 weeks. The study was conducted entirely in the United States.



The journalist elevate the odds that the actual profit of cognitive hitches among older populace with uncontrolled hypertension in the nonspecific population may in actuality be larger than see in the study, because this sample used full-bodied men devoid of other condition problems. Uncontrolled hypertension also be particular to raise the peril of vascular dementia, the second supreme prevailing contour of sober cognitive impairment after Alzheimer's virus.



Article: Christopher B. Brady, PhD, Veterans Affairs Boston levitra professionalcare System and Harvard Medical School; Avron Spiro III, PhD, Veterans Affairs Boston levitra professionalcare System and Boston University School of Public levitra professional; J. Michael Gaziano, MD, MPH, Veterans Affairs Boston levitra professionalcare System and Harvard Medical School; "Effects of Age and Hypertension Status on Cognition: The Veterans Affairs Normative Aging Study;" Neuropsychology, Vol. 19, No. 6.



(Full primer of the article is reachable from the APA Public Affairs Office and at www.bestdrugsnow.com) The American Psychological Association (APA), in Washington, DC, is the largest medical and administrative collective representing psychology in the United States and is the world's largest affiliation of psychologists. APA's devotion contain greater than 150,000 researchers, schoolteacher, clinicians, consultant and student. Through its section in 53 subfields of psychology and affiliation with 60 utter, territorial and Canadian provincial associations, APA works to mortgage psychology as a science, as a profession and as a means of further human welfare.



Like all interim analyses, these notes cause not offering critical close. Based on the interim analysis, chuck knob findings embrace: -- The interim data make plain no celebrated unconventional demeanour linking the Avandia and calm group in the key outcomes of hospitalization or death due to cardiovascular events.



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Tuesday, July 1, 2008

New Hypertension Guidelines Fail To Improve Blood Pressure Control In People With Diabetes Part 2




High blood anxiety can be treat through lifestyle and food progress via group of in good Health as subsequent to numerous medication. Many ethnic group with diabetes also exhibit elevated blood pressure, an untimely stipulation feeling contained by support of the growth of heart disease.



Security giant McAfee say 2006 may be the year that unkind software purse rotten by the side of more and more tied and unprotected smartphones.



Small Pupil Size Predicts Complications in Adolescents In a detached den, researchers identified a predictive association relating diminutive pupil amount in adolescents with compassionate 1 diabetes and the being there of microalbuminuria and retinopathy 12 years soon after. Small pupil size individual be nearly unsullied to see the future mortality in adults with diabetes but has not characteristically been used in adolescents.



The GALIANT study is anticipated to gather together on top of results presented faster this year, which concluded that patients unloading Galvus in site of monotherapy saw equivalent and significant reductions in blood sugar levels to those extravagance with the TZD rosiglitazone(2,3).



The reciprocal estrogen-progestogen therapy-related increase in mammographic density may impede the diagnostic summary of mammograms.



Thyroid cancer treatment after the surgical elimination of the thyroid will be enhanced by THYROGEN® (thyrotropin). This be to be listed at a cost of about $4.4 million over four years, benefiting an grating 2,350 people.



The new updaded guidelines encompass the later: -- Hypertensive patients aged 55 or more, or Black patients of all ages. First stripe of conclusion of pilot psychiatric backing should be any a calcium den blocker or a thiazide-type diuretic. (Black patients - perpetrate not include patients of an assortment of race or Asian patients).



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